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Glutamate is the most pervasive neurotransmitter in the central nervous system (CNS). Despite this fact, no validated biological markers, or biomarker...Savoir plus
Technological advances in noninvasive neuroimaging, neurophysiology, genome sequencing, and other methods together with rapid progress in computationa...Savoir plus
Major depressive disorder (MDD) is recognized worldwide as a major cause of disability, morbidity, and mortality. According to the World Health Organi...Savoir plus
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Based on advances in biotechnology and neuroscience, non-invasive neuromodulation devices are poised to gain clinical importance in the coming years a...Savoir plus
Autism spectrum disorders (ASD) constitute a major public health problem, affecting one in every 150 children and their families. Unfortunately, there...Savoir plus
Neuroscience has made phenomenal advances over the past 50 years and the pace of discovery continues to accelerate. On June 25, 2008, the Institute of...Savoir plus
The Food and Drug Administration (FDA) now requires that all clinical trials for drugs that affect the central nervous system--including psychiatric d...Savoir plus
One of the largest treatment gaps for mental, neurological, and substance use (MNS) disorders in the world can be seen in Sub-Saharan Africa (SSA). Ac...Savoir plus
Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and ...Savoir plus
Millions of people in sub-Saharan Africa suffer from mental, neurological, and substance use (MNS) disorders, and most do not have the resources to ob...Savoir plus
Nervous system diseases and disorders are highly prevalent and substantially contribute to the overall disease burden. Despite significant information...Savoir plus
Mood disorders - including depression and bipolar disorder - are common, disabling, and potentially lethal disorders, characterized by a shortened lif...Savoir plus
Many voluntary health organizations fund translational research. An increasing number of these organizations are looking at venture philanthropy as a ...Savoir plus
Chronic pain is one of the most prevalent, costly, and disabling health conditions in the United States. Estimates show that more than 11 percent of t...Savoir plus
Neuroinflammation is a burgeoning area of interest in academia and biopharma, with a broadly acknowledged role in many central nervous system (CNS) di...Savoir plus
While significant progress has been seen in fields such as cardiovascular medicine and cancer in improving patient stratification and developing targe...Savoir plus
On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop...Savoir plus
Neurodegeneration: Exploring Commonalities Across Diseases is the summary of a workshop hosted by the Institute of Medicine\'s (IOM\'s) Forum on Neuro...Savoir plus
Animals are widely used in neuroscience research to explore biological mechanisms of nervous system function, to identify the genetic basis of disease...Savoir plus
Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience...Savoir plus
From its very beginning, neuroscience has been fundamentally interdisciplinary. As a result of rapid technological advances and the advent of large co...Savoir plus
Pharmaceutical companies, academic researchers, and government agencies such as the Food and Drug Administration and the National Institutes of Health...Savoir plus