Fish Physiology, Volume 38 in this ongoing series, examines how the inherent potential of fish to express traits of economic value can be realized through aquaculture. Topics covered include the regulation of the reproductive cycle of captive fish, shifting carnivorous fish towards plant-based diets, defining the challenges, opportunities and optimal conditions for growth under intensive culture (including in Recirculating Aquaculture Systems), enhancing immune function and fish health during culture, identifying and managing maladaptive physiological responses to aquaculture stressors, establishing welfare guidelines for farmed fish, phenotypic and physiological responses to genetic modification, Zebrafish as a research tool, and the aquaculture of air-breathing fish.