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Brain Imaging in Substance Abuse

Research, Clinical, and Forensic Applications

Livre relié | Anglais | Forensic Science and Medicine
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Description

The last two decades have seen prodigious growth in the application of brain imaging methods to questions of substance abuse and addiction. Despite considerable advances in our understanding of the central effects of drugs provided by preclinical data, relatively little direct evidence was known of how substances of abuse affect the brain and other eNS processes in humans. Brain imaging techniques have allowed access to the human brain and enabled the asking of questions never before imagined. The positron emission tomography (PET) data ofVolkow and her colleagues in the late 1980s, showing the uptake and time course of cocaine's binding in the human brain, revealed for the first time the distinct sites of action of this drug. This work was extremely important because it showed clearly, through imaging a drug in the brain of a living human, that the time course of its action paralleled the behavioral state of "high. " This study marked a turning point in our understanding of drug-brain-behav- ior interactions in humans. Many more investigations of drug effects on the structure and function of the human brain were soon to follow, leading to much better insights into brain systems. Brain imaging allowed for the direct assessment of structural and functional anatomy, biology, and chemistry in substance abusers.

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Editeur:

Contenu

Nombre de pages :
425
Langue:
Anglais
Collection :

Caractéristiques

EAN:
9780896037700
Date de parution :
29-09-00
Format:
Livre relié
Format numérique:
Genaaid
Dimensions :
187 mm x 263 mm
Poids :
1270 g

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