Description

Presenting the current knowledge on biomarkers for the early (i.e. sub-clinical) detection of disease and the methodologies used for detecting these biomarkers which are often present at very low concentrations in bodily fluids, this book makes an important contribution to the literature. Topics covered include biomarkers for the early detection of cancer, diabetes, and cardiac disease, as well as the emerging technologies and adaptation of existing technologies that make early detection possible, including mass spectrometry and metabolomic techniques. Although there have been many reviews and book chapters on the subject of biomarkers, none have focused purely on the early detection of disease in a way that combines our current knowledge of biomarkers with the key advances in technology required for their discovery and detection. This integrated approach will provide a key reference work for researchers, clinicians and students.