After undergoing a nano-tech procedure, Richie "Fabio" Fazio finds he is no longer able to kill for his underworld employers. When a man who has a suspicious knowledge of Fabio's past and abilities turns up on his door step, Fabio believes his worries are over. But his boss has a bigger plan in mind. A race to rule New York ensues, pitting underworld forces against each other and involving the doctors who changed both men. Meanwhile, Fabio's nemesis on the NYPD continues his watch of the man the police suspect is the notorious hit man, Dead-Eye Dick.