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Protein Folding in Silico

Protein Folding Versus Protein Structure Prediction

Livre relié | Anglais | Woodhead Publishing Biomedicine
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Description

Protein folding is a process by which a protein structure assumes its functional shape of conformation, and has been the subject of research since the publication of the first software tool for protein structure prediction. Protein folding in silico approaches this issue by introducing an ab initio model that attempts to simulate as far as possible the folding process as it takes place in vivo, and attempts to construct a mechanistic model on the basis of the predictions made. The opening chapters discuss the early stage intermediate and late stage intermediate models, followed by a discussion of structural information that affects the interpretation of the folding process. The second half of the book covers a variety of topics including ligand binding site recognition, the fuzzy oil drop model and its use in simulation of the polypeptide chain, and misfolded proteins. The book ends with an overview of a number of other ab initio methods for protein structure predictions and some concluding remarks.

Spécifications

Parties prenantes

Editeur:

Contenu

Nombre de pages :
240
Langue:
Anglais
Collection :

Caractéristiques

EAN:
9781907568176
Date de parution :
04-10-12
Format:
Livre relié
Format numérique:
Genaaid
Dimensions :
156 mm x 234 mm
Poids :
517 g

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