This book analyzes the competitiveness of European regions and presents forecasts for 2030 and 2100 under different climate scenarios. It examines the economic impact of climate change from a regional economic perspective and sheds light on various factors that influence regional competitiveness and development. Furthermore, the authors derive reflections on EU climate policy and policy recommendations from the empirical results, which will help both scientists and regional decision-makers to implement policy measures and develop successful adaptation processes for the regions and countries of the EU to climate change.