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Spectrophotometry in Pharmaceutical Analysis
Determination of Cefaclor in Formulations
Shabbir Ahmed, Akhtar Rasul, Zeeshan Masood
Livre broché | Anglais
48,45 €
+ 96 points
Description
A simple spectrophotometric method for determination of cefaclor in raw and dosage forms based on reaction with ninhydrin is developed, optimized and validated. The purple color (Ruhemenn's purple) resulted from the reaction was stabilized and measured at 560 nm.The method optimization was essential as many procedural parameters influenced the accuracy of determination all variables including the reagent concentration, heating time, reaction temperature, color stability period, and cefaclor/ninhydrin ratio were studied in order to optimize the reaction conditions. No interference was observed from common pharmaceutical adjuvant. The developed method is easy to use, accurate and highly cost-effective for routine studies relative to HPLC and other techniques.
Spécifications
Parties prenantes
- Auteur(s) :
- Editeur:
Contenu
- Nombre de pages :
- 100
- Langue:
- Anglais
Caractéristiques
- EAN:
- 9783844392715
- Date de parution :
- 22-11-11
- Format:
- Livre broché
- Format numérique:
- Trade paperback (VS)
- Dimensions :
- 152 mm x 229 mm
- Poids :
- 158 g
