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Systems Biological Approaches in Infectious Diseases
210,95 €
+ 421 points
Description
Systems biology and its impact on anti-infective drug development.- Applications of transcriptional profiling in antibiotics discovery and development.- Chemical genetics: An evolving toolbox for target identification and lead optimization.- Proteomic profiling of cellular stresses in Bacillus subtilis reveals cellular networks and assists in elucidating antibiotic mechanisms of action.- Elucidating the mode-of-action of compounds from metabolite profiling studies.- A subsystems-based approach to the identification of drug targets in bacterial pathogens.- Metabolic control analysis to identify optimal drug targets.- The protein network as a tool for finding novel drug targets.- Toxicogenomics applied to predictive and exploratory toxicology for the safety assessment of new chemical entities: a long road with deep potholes.- The application of the theory of biological robustness to complex host-pathogen systems .- Toward whole cell modeling and simulation: comprehensive functional genomics through the constraint-based approach.- Genomics of host-pathogen interactions
Spécifications
Parties prenantes
- Editeur:
Contenu
- Nombre de pages :
- 350
- Langue:
- Anglais
- Collection :
- Tome:
- n° 64
Caractéristiques
- EAN:
- 9783764375669
- Date de parution :
- 20-11-06
- Format:
- Livre relié
- Format numérique:
- Genaaid
- Dimensions :
- 173 mm x 239 mm
- Poids :
- 929 g
