When sisters Annabelle and Maisie argue over a toy, Mommy sends them outside for some fresh air. They encounter a very unusual cat---the Gigglepuss--who promises that he will "Tickle your fancy, tickle your toes, and you'll have giggles wherever you go." Sure enough, the girls can not stop giggling. At first, their parents are amused, but when they realize the girls can NOT stop, they take action. Follow these gigglers to the doctor's office to find out his unusual remedy. Will the Gigglepuss strike again?