Description

The antipsychotic drugs are being used mainly for treatment of schizophrenia. Schizophrenia is a mental disorder characterized by a breakdown of typical emotional responses. Modified drug delivery systems (MDDS) of antipsychotics offer advantages over conventional formulations in provison of convenience, side effects and efficacy. Extended Release tablet of Antipsychotic drug were prepared using varying ratios of drug and polymers were selected for the study. After fixing the ratio of drug and polymer to control the release of drug up to desired time, the release rates were modulated by combination of two different rates controlling material. The effect of polymer concentration and channelizer concentration were studied. Drug release was observed upto 24 hrs.