This book presents and defends an original and paradigm-shifting conception of formal science, natural science, and the natural universe alike, that's fully pro-science, but at the same time neither theological or God-centered, nor solipsistic or self-centered, nor communitarian or social-institution-centered, nor scientistic or science-valorizing, nor materialist/physicalist or reductive, nor-above all-mechanistic. It does this by presenting and defending what Robert Hanna calls the neo-organicist turn, including manifest realism and the three sub-parts of metaphysical organicism: liberal naturalism, mind-life continuity, and explanatory inversion, whereby mechanical systems are explained by grounding them in organic systems, and not the other way around. Or more briefly and simply put, the purpose of this book is to present and defend science for humans. As such, it will be highly interesting and profoundly relevant to graduate students and specialist researchers in philosophy and the formal-&-natural sciences.