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  7. Histophysiology of the Obesity-Diabetes Syndrome in Sand Rats

Histophysiology of the Obesity-Diabetes Syndrome in Sand Rats

Herwig Hahn Von Dorsche, Harald Schäfer, Milan Titlbach
Livre broché | Anglais | Advances in Anatomy, Embryology and Cell Biology | n° 130
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Description

1. 1 Experimental Diabetes in the Sand Rat 1. 1. 1 Zoology Experimental diabetes has been used in numerous animals, of which rodents have been predominant because of their ease of maintenance and handling (Herberg 1979), but some species of ape and monkey have also occasionally been used (Brunk 1971; Malaisse and Malaisse-Lagae 1970). Herberg et al. (1976) divided rodent species into two groups based on the similarity of their metabolic response to the induction of diabetes to the onset of diabetes mellitus in man. In one of these groups (mouse, Mongolian gerbil, Tuco tuca), the response of the metabolism to the induction of diabetes was similar to the changes seen in the onset of adult-type diabetes mellitus in man; while the other group, which included the sand rat, spiny mouse, Chinese hamster, and Djungarian hamster, responded to diabetes induction in a way suggestive of juvenile insulin-dependent diabetes. Such a subdivision is not without prob- lems, however, particularly since difference occur not only between the various species of a group (Herberg et al. 1976), but, in our experience, also between animals of the same species (for instance the sand rat). Hence, the zoology of animals used for experimental purposes must also be taken into account. 1 The sand rat is classified as follows: Species: obesus Genus: Psammomys Subfamily: Gerbillinae Family: Cricetidae Suborder: Myomorpha Order: Rodentia Subclass: Placentalia Class: Mammalia Subphylum: Vertebrata Phylum: Chordata Psammomys obesus was first described by the zoologist P. J.

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Contenu

Nombre de pages :
95
Langue:
Anglais
Collection :
Tome:
n° 130

Caractéristiques

EAN:
9783540579137
Date de parution :
15-06-94
Format:
Livre broché
Format numérique:
Trade paperback (VS)
Dimensions :
156 mm x 234 mm
Poids :
158 g

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