Perfect Dream is about friendships. Annie meets Vincent van Gogh, Clarence Mahan, Tommy C. Berry, and Eugene Wheeler. Each contribute to her life. Vincent and Clarence are ghosts. Eugene is also a ghost but in limbo and regressing in time.
Annie is also planning to live in Oregon with Chuck. Annie loves irises. She also enjoys writing. She helps Tommy and Eugene with the Alcoholics Anonymous program of recovery. Annie bonds with Eugene the most. The two of them have a past to resolve.
Tommy and Annie work together in a laboratory in Oregon. This is one more facet of her life. Vincent with flowers, especially iris, Clarence and his association with writing and irises, Tommy with A.A. and work, and Eugene with alcoholism and bipolar illness all unfold in this book.