•  Retrait gratuit dans votre magasin Club
  •  7.000.000 titres dans notre catalogue
  •  Payer en toute sécurité
  •  Toujours un magasin près de chez vous     
  •  Retrait gratuit dans votre magasin Club
  •  7.000.000 titres dans notre catalogue
  •  Payer en toute sécurité
  •  Toujours un magasin près de chez vous
  1. Accueil
  2. Livres
  3. Sciences humaines
  4. Sciences
  5. Biologie
  6. Sciences de la vie
  7. Acute Lymphoblastic Leukemia (All) and Interferon Beta-1 Gene

Acute Lymphoblastic Leukemia (All) and Interferon Beta-1 Gene

Madiha Kanwal, Muhammad Jawad Khan, Abdul Rauf Shakoori
Livre broché | Anglais
67,45 €
+ 134 points
Livraison sous 1 à 4 semaines
Passer une commande en un clic
Payer en toute sécurité
Livraison en Belgique: 3,99 €
Livraison en magasin gratuite

Description

Acute lymphoblastic leukemia (ALL) is a malignant disease caused by the abnormal growth and development of early non-granular white blood cells, or lymphoblasts. ALL occurs predominantly in children, peaking at 4 years of age. Interferons (IFNs) are the biological agents involved in the antiviral responses and the inhibition of tumor growth. In oncology, the IFNs are an important treatment options for a number of solid tumors and hematological malignancies. The IFN-β1gene consists of 840 bp and it lacks intron sequences. Seventy patients suffering from Childhood Acute Lymphoblastic Leukemia were studied and analyzed for mutation analysis of IFN-β1. So, 58.3% of the patients suffering from ALL were observed and compared with 41.7% normal DNA samples as control. PCR was performed and amplified gene products were detected on agarose gel and PAGE. Finally, SSCP was performed and mobility shift was observed in 7 out of 70 ALL samples. We observed that ALL disease typically develops in children ages 1-10 years old and is more prevalent in males than females. Mutation in the IFN-β1 gene was significantly related to 1-5 years in case of association of mutation with age.

Spécifications

Parties prenantes

Auteur(s) :
Editeur:

Contenu

Nombre de pages :
172
Langue:
Anglais

Caractéristiques

EAN:
9783659230417
Date de parution :
31-08-12
Format:
Livre broché
Format numérique:
Trade paperback (VS)
Dimensions :
152 mm x 229 mm
Poids :
258 g

Les avis